Identification of γ1 subunit of GABAA receptor in rat testis
نویسندگان
چکیده
منابع مشابه
GABAA Receptor Subunits in Rat Testis and Sperm
Background γ-Aminobutyric acid (GABA) is considered to be the predominant inhibitory neurotransmitter in mammalian central nervous systems (CNS). There are two major classes of GABA receptors: GABAARs and GABABRs. The GABAA receptor is derived from various subunits such as alpha1-alpha 6, beta1-beta 3, gamma1-gamma 4, delta, epsilon, pi, and rho1-3. Intensive research has been performed to und...
متن کاملgabaa receptor subunits in rat testis and sperm
background: γ-aminobutyric acid (gaba) is considered to be the predominant inhibitory neurotransmitter in mammalian central nervous systems (cns). there are two major classes of gaba receptors: gabaars and gababrs. the gabaa receptor is derived from various subunits such as alpha1-alpha 6, beta1-beta 3, gamma1-gamma 4, delta, epsilon, pi, and rho1-3. intensive research has been performed to un...
متن کاملJuvenile stress-induced alteration of maturation of the GABAA receptor α subunit in the rat
Profound evidence indicates that GABAA receptors are important in the control of physiological response to stress and anxiety. The a subunit type composition contributes significantly to the functional characterization of the GABAA receptors. The a2, a3, a5 subunits are predominately expressed in the brain during embryonic and early postnatal periods of normal rats, whilst a1 are most prominent...
متن کاملThe distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon.
The expression patterns of 13 GABAA receptor subunit encoding genes (alpha 1-alpha 6, beta 1-beta 3, gamma 1-gamma 3, delta) were determined in adult rat brain by in situ hybridization. Each mRNA displayed a unique distribution, ranging from ubiquitous (alpha 1 mRNA) to narrowly confined (alpha 6 mRNA was present only in cerebellar granule cells). Some neuronal populations coexpressed large num...
متن کاملPOSSIBLE INVOLVEMENT OF GABAA RECEPTOR SITES IN CATALEPSY
The present work was performed to show the possible interaction of GAB A, and GABAB receptors in catalepsy. The following results were obtained: 1- Muscimol (MUS), a GABAA agonist, induced catalepsy. This effect was dose-dependent. Baclofen (BAC), a GABAB agonist, had no effect in this respect. 2- Catalepsy induced by muscimol was potentiated by pretreatment of animals with bicuculline (BI...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Research
سال: 2002
ISSN: 1001-0602,1748-7838
DOI: 10.1038/sj.cr.7290107